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 | Volume 12, Number 1 (march- may 2007) |  | |
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 | Brain Tumor in Children: A Ten-years Study in Loghman Hospital |  |
 | | Author(s): Mehdizadeh M *, Zamani Gh and Samadian M | | Assistant Prof., Dept. of Pediatric Hematology & Oncology, Loghman hospital, Shaheed Beheshti Medical University Mehdizadeh@sbmu.ac.ir | | Study Type: Original | Subject: Medicine | | | Article abstract: | | Background: To determine whether the incidence and location of childhood CNS tumors in our patients follows the same pattern described in Western countries, we carried out this study.
Materials and Methods: We analyzed the data compiled from 50 children less than 15 years old with brain tumors operated in Department of Neurosurgery in our hospital between 1994 and 2004. Diagnosis was made based on pathology and in some cases through imaging. Vascular and metastatic lesions were excluded and the latest WHO classification of brain tumor pathology was applied.
Results: We found that 54% of all brain tumors were located in the supratentorial and 46% in the infratentorial region. Brain tumor was slightly more common in males (males 54% vs. females 46%). The most common tumor found in our patients was astrocytoma (43.9%), followed by meduloblastoma (26.8%), meningioma (14.6%), epandimoma (7.3%) craniopharyngioma (2.4%), epidermoid (2.4%) and dermoid(2.4%). However, in children between 5-10 years, meduloblastoma was the most common tumor. In this regards, the most common symptoms were headache and vomiting, respectively, whereas vomiting and increased head circumference were the most common ones in children under 5 years. The incidence in different age groups were as follows: 56% in 10-15 years old,28% in 5-9 years and 16% in under 5 years old. Astrocytoma was more common in female and meduloblastoma in male, relatively. Meningioma which has not been reported in western studies, was relatively common in our patients.
Conclusion: In our patients, the incidence and distribution of CNS tumors were somewhat different from various reports of western countries. Whether there is any regional difference in disease distribution between Middle East and the rest of the world, remains to be determined.
| | | Keywords: brain tumor, children, incidence, | |
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