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 | Volume 14, Number 2 (Jun& July 2009 2009) |  | |
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 | Staphylococcus aureus Carriage in Patients with Psoriasis |  |
 | | Author(s): Shahidi Dadras M, Toosi P, Sarrafi-rad N *, Kavand S and Mahmoud Robati R | | Skin Research Center, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tajrish, Shahrdari St, Tehran, Iran nimasarrafirad@yahoo.com | | Study Type: Original | Subject: Medicine | | | Article abstract: | | Background and Aim: The aggravating role of Staphylococcus aureus superantigens is well known in atopic dermatitis but has not yet been proven in psoriasis. The role of Staphylococcus aureus is emphasized in the initiation, maintenance and complications of psoriasis. We investigated the frequency of nasal, axillary, and perineal carriage of Staphylococcus aureus (S. aureus) in patients with psoriasis and its possible influence on the severity of the disease.
Materials and Methods: One hundred patients with the clinical diagnosis of psoriasis participated in the study. Cultures of the bacterial flora were obtained from the right and left axilla and nasal nares and perineum, inoculated on standard bacterial medium (blood agar), and incubated at 37°C degrees for 48 h.
Results: one hundred patients with the clinical diagnosis of psoriasis (42% female and 58% male) comprised the study group. Mean age of the patients was 41.1±17.1 years. 42% of the patients carried S. aureus of these, 32% were from the nose, 13% from axilla, and 11% from the perineum. Three patients were carrier in 3 sites. There was no significant difference in the severity of the disease between the carriers and non-carriers measured by the psoriasis area and severity index (PASI) Score.
Conclusion: It seems that the severity of psoriasis is not influenced by staphylococcal carrier state.
| | | Keywords: Psoriasis; Staphylococcus aureus; Carrier State; Colonization, | |
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